Design, synthesis, crystal structure, and herbicidal activity of novel pyrrolidine-2,4-dione derivatives incorporating an alkyl ether pharmacophore with natural tetramic acids as lead compounds

A series of pyrrolidine-2,4-dione derivatives incorporating a chainlike alkoxyalkyl moiety or substituted phenoxyethyl moiety were designed and synthesized based on natural tetramic acids. Some target compounds showed obvious herbicidal activities.