Arteriosclerotic cerebral small vessel diseases and sleep disturbances

Studies have shown that cerebral small vessel diseases can affect the mechanisms such as neural circuits, local cerebral blood flow changes, and neuroendocrine changes through brain damage, causing sleep disorders, and poststroke depression and brain atrophy caused by cerebral small vessel diseases may be associated with sleep disorders. In return, sleep disorders can damage the blood-brain barrier and cerebrovascular autoregulation function, and increase the risk of the occurrence of cerebrovascular disease. Both of them are interrelated, reciprocal causation, and commonly affect the prognosis and quality of life in patients. Key words: Cerebral Small Vessel Diseases; Intracranial Arteriosclerosis; Sleep; Sleep Apnea, Obstructive; Sleep Apnea Syndromes; Sleep Wake Disorders; Risk Factors