Antibacterial effect of anti-tuberculosis decoction against clinical isolated mycobacterium tuberculosis in vitro

Objective To study the antibacterial activity of anti-tuberculosis decoction against clinical isolated rifampicin drug-resistant mycobacterium tuberculosis (number: A) and rifampicin sensitive mycobacterium tuberculosis (number: B) in vitro. Methods Rifampicin was selected as a positive control medicine.Anti-tuberculosis decoction and rifampicin were respectively used to test the bacteria through absolute concentration method and the direct effect method, then recorded and analyzed the observation phenomenon. Results The MIC of anti-tuberculosis decoction for A, B was 64.00mg/mL by using the absolute concentration method, and the MIC of anti-tuberculosis decoction for A, B was 8.00mg/mL by using direct effect method. Conclusion Anti-tuberculosis decoction had a good antibacterial activity for rifampicin resistant mycobacterium tuberculosis and rifampicin sensitive mycobacterium tuberculosis in vitro. Key words: Anti-Tuberculosis decoction; Rifampicin; Mycobacterium tuberculosis; Antibacterial