Adverse reactions and safety analysis of spirometry

Objective To investigate the adverse reactions and safety in patients who underwent spirometry.Methods Adverse reactions of 996 patients who underwent spirometry in the lung function testing laboratory were assessed by questionnaire survey,Results A total of 294 adverse reactions were present in 270 patients (27.1％),of whom 24 subjects experienced two or three distinct adverse reactions.The incidence rate of adverse reactions was ordered as respiratory tract symptoms,neuromyic symptoms and laryngopharyngeal symptoms,with dyspnea ( 129 cases,13.0 ％),coughing (79 cases,7.9 ％) and vertigo (43 cases,4.3 ％ ) being most common.The incidence rate of dyspnea in patients with airway obstruction was significantly higher than those without airway obstruction ( P =0.000),and the rate increased as lung disfunction upgraded.Of 294 adverse reactions,81.0％ were mild,which could be ameliorated by resting,19.0％ (56/294) belonged to moderate,which could only be recovered through clinical intervention.No severe adverse reaction was reported.Conclusions Despite that spirometry may result in certain adverse reactions,this measurement remains safe provided that indications of teat were under rigorous clinical monitoring and emergency was managed in a timely manner. Key words: Spirometry; Forced vital capacity; Lung function testing; Adverse reaction; Safety