化学
齐墩果酸
异核单量子相干光谱
结合
二维核磁共振波谱
立体化学
查尔酮
核磁共振波谱
质子核磁共振
阿卡波糖
组合化学
有机化学
酶
病理
替代医学
数学分析
医学
数学
作者
Chu Tang,Linhui Zhu,Jun Li,Rui Qin,Chang Liu,Yu Chen,Guangzhong Yang
摘要
Five new conjugates of oleanolic acid derivatives and chalcones have been designed and synthesized. The structure elucidation of these conjugates was accomplished by using extensive 1D ( 1 H, 13 C) and 2D NMR spectroscopic studies (COSY, HSQC and HMBC); and α ‐glucosidase inhibitory activity is reported for these conjugates. Compound 2b (IC 50 = 47.5 µ m ) displayed much stronger activity than oleanolic acid and acarbose. Copyright © 2012 John Wiley & Sons, Ltd.
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