Systematic reviews and meta-analyses in animal model research: as necessary, and with similar pros and cons, as in patient research

Systematic reviews and meta-analyses (SRMAs) are very useful tools for evaluating the status of research on a given topic in medical sciences [1, 2]. Although SRMAs are primarily used in clinical investigation, the methodologies underlying SRMAs can also be readily used to assess extant data focused on research in animal models of disease [3]. Systematic reviews and meta-analyses from research data in animal models of disease are useful for translational medicine