吡唑酮类
化学
对映体
对映选择合成
催化作用
立体化学
有机化学
组合化学
作者
Nick Wannenmacher,Martin Heberle,Xin Yu,Aysegül Demircan,Daniel M. Wanner,Camilla Pfeffer,René Peters
标识
DOI:10.1002/adsc.202200185
摘要
Abstract A diastereospecific enantiodivergent allylation of pyrazolones is reported which is catalyzed by a planar chiral pentaphenylferrocene based palladacycle. With the same catalyst batch both product enantiomers were selectively available. The method is applicable to structurally diverse substrates and gave products with enantiomeric excesses between 85 and 94%. In addition, we could show that pyrazolones are transformable into β‐aminoamides. magnified image
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