化学
点击化学
尿苷
荧光团
炔烃
组合化学
核苷
立体化学
荧光
有机化学
核糖核酸
生物化学
催化作用
基因
量子力学
物理
作者
Huixia Zhou,Yuanyuan Li,Sheng Wang,Li Wang,Rui Wang
标识
DOI:10.1016/j.tetlet.2022.153678
摘要
We report here the 2′-azidomethyl modified uridine nucleoside (2′-AmU) can be efficiently synthesized and employed in the labeling study of nascent deoxynucleic acid of interest using fluorophore with alkyne (DBCO-Cy5). This new DNA labeling tool using uridine variant (2′-AmU) displays intensive application potential considering the several advantages it possesses, including readily available, rather small size (minimal perturbation), reversible regulation and easy subjected to click reaction.
科研通智能强力驱动
Strongly Powered by AbleSci AI