A Review of Chalcones: Synthesis, Reactions, and Biological Importance

Chalcones are considered an important scaffold in organic compounds. Many of their derivatives have a lot of applications. Therefore, this review was covered some synthesis methods of chalcones such as Claisen-Schmidt's condensation, coupling reaction, continuous-flow deuteration reaction, and other reactions. Also, some reactions were discussed such as the synthesis of seven, six, and five-membered ring heterocyclic compounds. Moreover, some of their biological applications were mentioned like antimicrobial, anticancer, anti-inflammatory, antioxidants, and others with some details.