催化作用
密度泛函理论
锌
化学
沸石咪唑盐骨架
咪唑酯
Atom(片上系统)
纳米材料
组合化学
同种类的
纳米技术
材料科学
光化学
计算化学
有机化学
金属有机骨架
热力学
物理
嵌入式系统
吸附
计算机科学
作者
Bolong Xu,Hui Wang,Weiwei Wang,Lizeng Gao,Shanshan Li,Xueting Pan,Hongyu Wang,Hailong Yang,Xiangmin Meng,Qiuwen Wu,Lirong Zheng,Shen‐Ming Chen,Xinghua Shi,Kelong Fan,Xiyun Yan,Huiyu Liu
标识
DOI:10.1002/anie.201813994
摘要
Abstract Single‐atom catalysts (SACs), as homogeneous catalysts, have been widely explored for chemical catalysis. However, few studies focus on the applications of SACs in enzymatic catalysis. Herein, we report that a zinc‐based zeolitic‐imidazolate‐framework (ZIF‐8)‐derived carbon nanomaterial containing atomically dispersed zinc atoms can serve as a highly efficient single‐atom peroxidase mimic. To reveal its structure–activity relationship, the structural evolution of the single‐atom nanozyme (SAzyme) was systematically investigated. Furthermore, the coordinatively unsaturated active zinc sites and catalytic mechanism of the SAzyme are disclosed using density functional theory (DFT) calculations. The SAzyme, with high therapeutic effect and biosafety, shows great promises for wound antibacterial applications.
科研通智能强力驱动
Strongly Powered by AbleSci AI