Synthesis of Aryl- and Alkylquinones through Rhodium-Catalyzed C–C Coupling under Mild Conditions

A direct arylation, alkylation of quinones with aryl and alkyl boronic acids through rhodium-catalyzed C–C coupling has been developed under mild conditions. [Cp*RhCl₂]₂ was shown to be the most effective catalyst for the transformation. More importantly, good to excellent yields were obtained under room temperature and base-free conditions. This reaction provides a practical, efficient method for the synthesis of aryl- and alkylquinones.