Discussion of Triptolide Suppression Mechanism of TNF-α in Rheumatoid Arthritis Synovial Membrane Newborn Blood Vessel

Objective:In order to understand effects of Triptolide on TNF-α in rheumatoid arthritis synovial organization,the tripterygium wilfordii treatment mechanism of rheumatoid arthritis was to discuss.Methods:The immunohistochemical techniques were used to detect expression of TNF-α in the AA rats in the organization of the synovial organization,and the effects of tripterygium wilfordii were observed.Results:The tripterygium wilfordii group showed positive TNF-α cells,compared the experimental group there was significant difference(P0.05).Conclusion:Triptolide can reduce the expression of TNF-α in synovial organizations and inhibit angiogenesis,playing a therapeutic role.