Evaluation of risk factors affecting the postoperative muscle weakness crises in patients with thymic lesion and myasthenia gravis

Objective To evaluate the risk factors affecting the postoperative muscle weakness crises.Methods Analysed clinical data of patients with thymoma resection retrospectively.Results The patients with type of Osseman(P = 0.010),preoperative course(P 0.001),dose of pyridostigmine(P 0.001),happened muscle weakness crises before operation(P 0.001),postoperative lung infection(P 0.001) and without usage of plasma(P = 0.012) exerted effects on postoperative muscle weakness crises.Type of Osseman(P = 0.014),dose of pyridostigmine before surgery(P 0.001) and without usage of plasma(P = 0.033) were independent risk factors for muscle weakness crises.Conclusions Patients with high type of Osseman,large dose of pyridostigmine before surgery and without usage of plasma easy to have postoperative muscle weakness crises.