Characteristics of TCM syndromes and lipid level in patients with insulin resistance of type 2 diabetes

Objective To investigate the characteristics of TCM syndromes and lipid level in patients with insulin resistance of type 2 diabetes.Methods The patients(n=99) with type 2 diabetes were divided into the group of insulin resistance and the group of non-insulin resistance according to insulin resistance index(HOMA-IR).The levels of fasting plasma glucose(FPG),fasting insulin(FINS),total cholesterol(TC) and triglyceride(TG) were detected in two groups respectively.The insulin sensitivity index(ISI) and body mass index(BMI) were calculated and TCM syndromes were determined.Finally the anxious integrals of all patients were judged and compared with those of normal persons.Results The levels of FPG,FINS,TG and BMI all increased and ISI decreased in the group of insulin resistance compared with those in the group of non-insulin resistance.The comparison in TCM syndromes between two groups was not different but there was significantly different in syndrome construction inside the group of insulin resistance.The patients with excess syndrome were less than those with deficient syndrome and those with the syndrome combined deficiency with excess.There was no significant different in syndrome construction inside the group of non-insulin resistance.Conclusion The characteristic of insulin resistance of type 2 diabetes is that the patients with deficiency syndrome is less than those with the syndrome combined deficiency with excess.The insulin resistance of type 2 diabetes is correlated to TG level.