Individual immunosuppression regime in liver transplant recipients with high risk factors

Objective To evaluate the significance of individual immunosuppression regime in liver transplant recipients with high risk factors. Methods Every liver transplant recipient received different immunosuppression regime based on different clinical conditions. Renal failure, acute rejection, bacterial, fungal and cytomegaloviral infection rate and hospital mortality were compared among the high risk recipients ( n =20) with individual immunosuppression regime, high risk recipients ( n =22) with routine immunosuppression regime and common recipients ( n =26) with routine regime. Results Renal failure, bacterial, fungal infection rate and hospital mortality were significantly different between high risk patients with individual immunosuppression regime and those with routine immunosuppression regime ( P 0.05 ). There was no significant difference in acute rejection and cytomegaloviral infection rate between two groups ( P 0.05 ). There was no significant difference in the above observed parameters between high risk recipients with individual immunosuppression regime and common recipients with routine regime ( P 0.05 ). Conclusion Individual immunosuppression regime can prolong the survival of the recipients with high risk factors and is proved to be more safe and reliable.