On the Role of Screening for Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease

Intracranial aneurysm (ICAN) formation is a well-known complication in patients with autosomal dominant polycystic kidney disease (ADPKD). In these patients, aneurysms are thought to form as a consequence of abnormal polycystin protein expression in vascular myocytes, which impairs the structural