Isolation and identification of chemical constituents from leaves of Gynura procumbens(Lour.)Merr.

Objective To study the chemical constituents of leaves of Gynura procumbens(Lour.)Merr.Methods The compounds were isolated by chromatography on silica gel colunm,C18 reversed-phase column,Sephadex LH-20 column and HPLC,and their structures were determined on the basis of spectral analysis.Results Seven compounds were obtained and identified as β-sitosterol-3-O-gentiobioside(1),indole-3-carboxylic acid(2),grasshopper ketone(3),β-sitosterol(4),drummondone A(5),n-dotriacontanol(6),drummondone B(7).Conclusions Compounds 1-3,5 and 7 are isolated from Gynura genus firstly,while compounds 4 and 6 are isolated from Gynura procumbens(Lour.)Merr.for the first time.