Clinical observation of diacerein combined with sodium hyaluronate in the treatment of knee osteoarthritis

Objective: To approach the curative effect of diacerein combined with sodium hyaluronate in the treatment of knee osteoarthritis.Methods: Forty-seven patients with knee osteoarthritis were randomly divided into two groups,with 25 patients in the treatment group treated with diacerein and sodium hyaluronate and 22 patients in the control group injected with sodium hyaluronate,12 weeks later.VAS score,WO-MAC score were evaluated and therapeutic effects were compared before and after treatment in the two groups.Results: In the treatment group,the mean VAS and WOM-AC were improved after treatment(P 0.05),whilt in the control group,only VAS score declined further(P 0.05).In the treatment group,the excellent rate was significantly higher than that in the control group.Conclusion: Diacerein combined with sodium hyaluronate has a very marked therapeutic effect on knee osteoarthritis,which should be widely used for the treatment of knee osteoarthritis in clinic.