Detection and analysis of integrons in imipenem-resistant clinical isolates of Pseudomonas aeruginosa

Objective to investigate the distribution of imipenem-resistant clinical isolates of Pseudomonas aeruginosa.Methods Bacterial identification and susceptibility were tested by Micro-Walkway-96 automatic bacterial instrument.The integrons,in 120 imipenem-resistant and 80 imipenem-sensitive of Pseudomonas aeruginosa,were detected by PCR.Results Class Ⅰand class Ⅲ integron were 81.7%(98/120),1.7%(2/120) in imipenem-resistant Pseudomonas aeruginosa,respectively.class Ⅱ integron were not detected.And class Ⅰ integron rate was 21.3%(17/80) in 80 strains of imipenem-sensitive of Pseudomonas aeruginosa,but class Ⅱ and class Ⅲ integron were not detected.?Integron positive of Pseudomonas aeruginosa clinical antibiotic resistance significantly higher than integron negative of Pseudomonas aeruginosa,and the former multi-drug resistance is more serious.Conclusion Our results revealed that ClassⅠ integron were widespread in imipenem-resistant clinical isolates of Pseudomonas aeruginosa.