Moving Forward Liquid Biopsy in Early Liver Cancer Detection

Summary: Early cancer detection is an attractive and promising application for liquid biopsy that might revolutionize cancer screenings. In this issue of Cancer Discovery, Foda and colleagues expand the potential utility of a machine learning fragmentome-based model, called DELFI, for detecting liver cancer in high-risk patients. See related article by Foda et al., p. 616 (5).