Transition Metal‐Catalyzed Dearomative Vinylation of Electron Rich Benzenes, Naphthalenes and Indoles with Alkynes

Abstract Dearomatization reactions are among the most efficient chemical processes, combining atom economy, stereospecificity and the ability to generate molecular complexity in a single step. Dearomative vinylation reactions provide a synthetic connection between readily available, simple aromatic starting materials and more unsaturated alkynes. The last decade has witnessed a steady increase in the development of transition metal‐catalyzed dearomative vinylation methods of electron rich aromatic compounds with alkynes, providing new synthetic approaches to high‐value building blocks and natural products. This review aims to serve as a comprehensive reference for work in transition metal‐catalyzed dearomative vinylation reactions of electron rich aromatic compounds with alkynes. magnified image