美托洛尔
肥厚性心肌病
心脏病学
梗阻性心肌病
医学
内科学
作者
Pablo García‐Pavía,Martin S. Maron,Ahmad Masri,Béla Merkely,Michael E. Nassif,María Luisa Peña‐Peña,Roberto Barriales‐Villa,Ozlem Bilen,Melissa Burroughs,Brian Claggett,Juan Pablo Costabel,Edileide de Barros Correia,Anne M. Dybro,Perry Elliott,Sheila M. Hegde,Neal K. Lakdawala,Gregory D. Lewis,Amy Mann,Zi Michael Miao,Ajith Nair
标识
DOI:10.1056/nejmoa2504654
摘要
Among patients with symptomatic obstructive HCM, aficamten monotherapy was superior to metoprolol monotherapy in improving peak oxygen uptake and hemodynamics and decreasing symptoms. (Funded by Cytokinetics; MAPLE-HCM ClinicalTrials.gov number, NCT05767346.).
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