四分位数
医学
糖尿病
优势比
置信区间
逻辑回归
人口
内科学
横断面研究
人口学
内分泌学
环境卫生
病理
社会学
作者
Wu Chen,Chenxia Ren,Yingda Song,Huifang Gao,Xin Pang,Lianyun Zhang
标识
DOI:10.3389/fendo.2023.1148417
摘要
Background The relationship between oxidative balance score (OBS) and diabetes remains poorly understood and may be gender-specific. We conducted a cross-sectional study to investigate the complex association between OBS and diabetes among US adults. Methods Overall, 5,233 participants were included in this cross-sectional study. The exposure variable was OBS, composed of scores for 20 dietary and lifestyle factors. Multivariable logistic regression, subgroup analysis, and restricted cubic spline (RCS) regression were applied to examine the relationship between OBS and diabetes. Results Compared to the lowest OBS quartile group (Q1), the multivariable-adjusted odds ratio (OR) (95% confidence interval (CI) for the highest OBS quartile group (Q4) was 0.602 (0.372–0.974) ( p for trend = 0.007), and for the highest lifestyle, the OBS quartile group was 0.386 (0.223–0.667) ( p for trend < 0.001). Moreover, gender effects were found between OBS and diabetes ( p for interaction = 0.044). RCS showed an inverted-U relationship between OBS and diabetes in women ( p for non-linear = 6e−04) and a linear relationship between OBS and diabetes in men. Conclusions In summary, high OBS was negatively associated with diabetes risk in a gender-dependent manner.
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