Trends of Alzheimer’s Disease and Other Dementias with Socioeconomic Insights: An Age-Period-Cohort Analysis and Forecasts for 2046

We found a steady increase in incidence worldwide, with the greatest increase in high-middle SDI regions. The incidence is declining in areas with high SDI, and higher levels of socioeconomic development have a protective effect against ADOD. Incidence is increasing in younger age groups. Therefore, we believe that improving the level of social and economic development and formulating relevant targeted policies are helpful for the prevention of ADOD. Focusing on the trends in disease incidence across different economic development regions will enable more targeted strategies to address the burden of disease.