尼奥体
胶束
脂质体
自愈水凝胶
药物输送
药品
纳米颗粒
毒品携带者
前药
纳米医学
纳米技术
材料科学
化学
药理学
膜
有机化学
水溶液
医学
生物化学
小泡
作者
Reshma Joy,Jinu George,Franklin John
标识
DOI:10.1002/slct.202104045
摘要
Abstract Polymeric nanoparticles, micelles, niosomes, hydrogels and liposomes represent effective drug carriers having huge potential for medical and pharmaceutical applications. These systems remain the most important area in medicinal chemistry research. The aforementioned biomaterials can effectively encapsulate and release diverse hydrophobic/hydrophilic therapeutic molecules including drugs and prodrugs. Applications of these carrier systems extend to nucleic acids, antibodies and proteins which could be released sustainably. Since these systems fall in the nano dimension, they are capable of enhancing the therapeutic efficacy of bioactive molecules besides enabling them to accumulate preferentially at the target site. Furthermore, these systems can protect the encapsulated drug from degradation, thereby increasing the therapeutic value of the drug candidate and reducing systemic toxicity. In this review, we illustrate the preparative methods and actions of these five drug delivery systems.
科研通智能强力驱动
Strongly Powered by AbleSci AI