骨不连
小泡
基质(化学分析)
矿化(土壤科学)
病理
细胞
化学
超微结构
细胞生物学
解剖
生物
膜
医学
生物化学
有机化学
氮气
色谱法
作者
Daniela Elena Quacci,Carlo Dell’Orbo,Mauro Salvi,Pietro Bartolozzi,M Misasi
出处
期刊:PubMed
日期:1991-01-01
卷期号:6 (1): 87-93
被引量:3
摘要
A histological study on the tissue of nonunion of tibias of two young patients was performed to evaluate the ability of cells to start the mineralization of the matrix. The observations can be summarized as follows: 1) Tissue vessels often appear occluded by thrombotic material; 2) Fibroblasts and chondrocytes found in the nonunion tissue seemed normal, with a good secretion apparatus; 3) The cell membranes were able to produce matrix vesicles; 4) Matrix vesicles and cell membrane looked positive to ALPase reaction, 5) Hydroxyapatite crystals could be observed in the cell matrix or inside matrix vesicles. It may be concluded that cells populating nonunion tissue are well equipped to induct the mineralization of the matrix, but the absence of a blood supply, enough to bring them a normal calcium amount, is the real reason for the nonunion.
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