Quantification of Acute Myocardial Damage Secondary to Implantation of Electrodes for the Left Bundle Branch Area Pacing.

espanolAntecedentes: a diferencia de la estimulacion ventricular derecha tradicional, la estimulacion del area de la rama izquierda del haz (LBBAP) se logra con una implantacion mas profunda del electrodo y mas intentos. Sin embargo, el dano miocardico no esta claro en LBBAP. Objetivo: El objetivo del estudio fue observar el cambio de la troponina T y explorar posibles factores asociados a un mayor dano miocardico en BRI. Metodos: Los pacientes con indicacion de implante de marcapasos fueron sometidos a intentos de BRI mediante el metodo del tabique transventricular. Los niveles de troponina T se determinaron antes de la operacion, 12 hy 1 semana despues de la operacion. Se registraron y analizaron parametros intraoperatorios y de seguimiento. Resultados: En total, se logro LBBAP exitoso en 126 pacientes. Los niveles de troponina T aumentaron significativamente a las 12 h despues de la operacion en comparacion con los anteriores a la operacion (96,45 ± 11,07 [69,06] frente a 16,59 ± 1,84 [11,92] ng / L, p Conclusiones: El dano miocardico de LBBAP fue clinicamente significativo. El numero de intentos fue un factor independiente relacionado con el dano miocardico. EnglishBackground: Different from the traditional right ventricular pacing, the left bundle branch area pacing (LBBAP) is accomplished with deeper lead implantation and more attempts. However, myocardial damage is unclear in LBBAP. Objective: The objective of the study was to observe the change of troponin T and explore possible factors associated with greater myocardial damage in LBBAP. Methods: Patients with an indication for pacemaker implantation underwent attempts for LBBAP by transventricular septal method. Levels of troponin T were determined before operation, 12 h and 1 week after the operation. Parameters of intraoperation and follow-up were recorded and analyzed. Results: In total, successful LBBAP was achieved in 126 patients. The levels of troponin T increased significantly at 12 h after the operation compared with those before operation (96.45 ± 11.07 [69.06] vs. 16.59 ± 1.84 [11.92] ng/L, p Conclusions: Myocardial damage of LBBAP was clinically significant. The number of attempts was an independent factor related to the myocardial damage.