银屑病
长非编码RNA
生物
计算生物学
基因
转录调控
基因表达调控
核糖核酸
基因表达
生物信息学
遗传学
免疫学
作者
Jiankun Song,Yin Su,Wei Li,Xiaodong Li,Yue Luo,Ying Luo,Meng Xing,Bin Li,Le Kuai
标识
DOI:10.1097/cm9.0000000000001243
摘要
Abstract Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating mechanisms and functions of lncRNAs in psoriasis, especially focusing on the role of lncRNAs in keratinocytes, T cells, and dendritic cells.
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