生命银行
医学
乳腺癌
肿瘤科
癌症
内科学
队列
队列研究
作者
H Cai,Liyuan Liu,Fei Wang,H L Bao,Zhigang Yu,Lan Wang,Liwen Fang,Lei Xu,Rongming Wang,W Huangfu,C M Ye,G S Yin,Xuening Duan,H Y Jia
出处
期刊:Chinese journal of epidemiology
日期:2020-12-10
卷期号:41 (12): 2053-2058
标识
DOI:10.3760/cma.j.cn112338-20200507-00697
摘要
Objective: Biobank construction plays an irreplaceable role in the research of accurate prevention and treatment of diseases. Shared biobank network based on a large crowd queue is the way of the future. This subject is one of the key contents of national precision medicine Breast Cancer Cohort Study in Chinese Women: (BCCS-CW) , aiming to solve the bottleneck of insufficient standardization and sharing. Methods: The establishment of entity library-information library-extension library , the widely Shared network of biobank of breast cancer specific disease cohort, and the establishment of strict standard setting and quality control standard to construct the standardized biobank. Results: This biobank provides a shared biobank resource for breast cancer risk assessment, prediction and early warning, early screening, classification, individualized treatment, efficacy and safety prediction and monitoring and other accurate prevention and treatment programs and clinical decision-making system research. Conclusion: The data of this biological sample bank is refined and complete, and the sample size of cases is sufficient, which can meet the research needs of medical big data, genomics, metabonomics, epigenetics and other fields.
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