生物
转录因子
bZIP域
亮氨酸拉链
平动调节
翻译后调节
细胞生物学
基因表达调控
遗传学
ATF3
计算生物学
基因
转录调控
基因表达
翻译(生物学)
发起人
信使核糖核酸
作者
Katia Schütze,Klaus Harter,Christina Chaban
标识
DOI:10.1016/j.tplants.2008.03.002
摘要
The post-translational regulation of transcription factors plays an important role in the control of gene expression in eukaryotes. The mechanisms of regulation include not only factor modifications but also regulated protein-protein interaction, protein degradation and intracellular partitioning. In plants, the basic-region leucine zipper (bZIP) transcription factors contribute to many transcriptional response pathways. Despite this, little is known about their post-translational regulation. Recent findings suggest that plant bZIP factors are under the control of various partially signal-induced and reversible post-translational mechanisms that are crucial for the control of their function. However, the fact that, to date, only a few plant bZIPs have been analyzed with respect to post-translational regulation indicates that we have just identified the tip of an iceberg.
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