克罗恩病
单核苷酸多态性
节点2
医学
炎症性肠病
硫唑嘌呤
胃肠病学
疾病
基因型
内科学
遗传学
基因
生物
作者
Isabelle Cleynen,Juan R. González,Carolina Figueroa,André Franke,Dermot McGovern,Martin Bortlík,Bart J. A. Crusius,Maurizio Vecchi,Marta Artieda,Magdalena Szczypiorska,Johannes Bethge,David Arteta,Edgar Ayala,Silvio Danese,R. A. van Hogezand,Julián Panés,Salvador A. Peña,Milan Lukáš,Derek P. Jewell,Stefan Schreiber
出处
期刊:Gut
[BMJ]
日期:2012-12-21
卷期号:62 (11): 1556-1565
被引量:263
标识
DOI:10.1136/gutjnl-2011-300777
摘要
This large multicentre cohort study has found several genetic and clinical factors influencing the clinical course of CD. NOD2 and early immunomodulator use are the clinically most meaningful predictors for its clinical course.
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