化学
氧化剂
多米诺骨牌
酒
氧化磷酸化
酒精氧化
有机化学
组合化学
级联反应
催化作用
生物化学
作者
Sambasivarao Kotha,Govindasamy Sekar
标识
DOI:10.1016/j.tetlet.2015.09.053
摘要
An efficient method for the synthesis of α-keto amides using 2-iodoxybenzoic acid (IBX) promoted domino alcohol oxidation and oxidative amidation reaction sequence between 2-oxoalcohols and amines under metal-free conditions is developed. In this protocol, IBX is used as an oxidizing agent to synthesize the α-keto amides, which makes this methodology highly efficient, practical, and environmentally benign.
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