A 66-year-old man with a diagnosis of acute myeloid leukemia (AML) type M4 in 2017 who had undergone allogeneic hematopoietic stem cell transplantation in January 2018 presented with painless, nontender left hemiscrotal swelling.The patient underwent unilateral radical orchiectomy and histopathology revealed myeloperoxidase-, CD33-, and CD117positive and CD34-negative infiltration of AML in the testis and local spread into the spermatic cord, rete testis, epididymis, tunica albuginea, and the surrounding soft tissue suggesting myeloid sarcoma (MS).F18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) after left orchiectomy depicted moderate hypermetabolic metastatic retrocrural and paraaortic lymph nodes and multiple intense hypermetabolic foci along the course of the left testicular