电化学发光
过氧二硫酸盐
化学
硼
纳米技术
量子点
生物相容性
检出限
催化作用
材料科学
色谱法
有机化学
作者
Man-Fei Sun,Jiali Liu,Ying Zhou,Jiaqi Zhang,Yaqin Chai,Zhaohui Li,Ruo Yuan
出处
期刊:Analytical Chemistry
[American Chemical Society]
日期:2020-10-15
卷期号:92 (21): 14723-14729
被引量:34
标识
DOI:10.1021/acs.analchem.0c03289
摘要
Herein, the boron radical active sites of boron carbon oxynitride quantum dots (BCNO QDs) are electrically excited to produce boron radicals (B•) for catalyzing peroxydisulfate (S2O82–) as a coreactant to accelerate the generation of abundant sulfate radicals (SO4•–) for significant enhancement in the electrochemiluminescence (ECL) efficiency of BCNO QDs, which overcome the defect of traditional carbon-based QDs with low ECL efficiency. Impressively, under extremely low concentration of S2O82– solution, the BCNO QDs/S2O82– system could exhibit high ECL emission, realizing environmental friendliness and excellent biocompatibility for sensitive bioanalysis. As a proof-of-concept, BCNO QDs, a new generation of ECL emitters with high ECL efficiency, were successfully used in the ultrasensitive determination of microRNA-21, which pushes the exploration of new ECL emitters and broadens the application in the field of clinical diagnosis, ECL imaging, and molecular devices.
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