PM234 Carotid ultrasound: possible contribution to non-invasive diagnostic algorithms of coronary artery disease

Although allergen-specific immunotherapy (ASIT) in patients with airborne allergy is not a life-saving therapeutic method, it may, however, significantly affect the patient's quality of life and the course of IgE-dependent allergy (type I allergy), and especially prevent development of new allergies and asthma. The presented position paper addresses immunotherapy employed in patients allergic solely to airborne allergens. The currently understood ASIT mechanisms unambiguously point to the fact that it affects the immune system on the regulatory level. For this reason, we should consider its possible effect on the course of the disease in patients with concomitant immune diseases and especially autoimmune diseases (type II, III, and IVa immune reactions). The position paper aims at verifying the hypothesis: "whether allergen-specific immunotherapy may lead to development or intensification of hypersensitivity reaction" in five separate groups of patients with autoimmune disorders.