SEPARATION OF ENANTIOMERS OF DRUGS BY CAPILLARY ELECTROPHORESIS .1. GAMMA-CYCLODEXTRIN AS CHIRAL SOLVATING AGENT

Enantiomer separation was studied for a set of 57 chiral drugs. With gamma-cyclodextrin as chiral solvating agent in capillary zone electrophoresis, seven enantiomeric pairs could be separated without recoursing to an optimization procedure. Possible interaction mechanisms between selector and selectand molecules are briefly discussed.