Evalution of tetracyclines' antimicrobial susceptibility test for Stenotrophomonas maltophilia

Objective To investigate the resistance of Stenotrophomonas maltophilia using disc duffusion method and broth dilution method,which provide drug sensitivity results for clinically isolated Stenotrophomonas maltophilia and information on the difference of two methods. Methods Examining 28 strains of clinically isolated Stenotrophomonas maltophilia by the methods of disc diffusion and broth dilution,the diameters of the inhibition zones and the MIC values were measured.Results The susceptibility results of doxycycline and minocycline were better in curing Stenotrophomonas maltophilia infection;There was good relationship between K-B method and broth dilution method.Conclusion Doxycycline and minocycline can be chosen to cure Stenotrophomonas maltophilia infection clinically;K-B method can used to examine the drug sensitivity of Stenotrophomonas maltophilia to tetracyclines.