Objective To understand the pollution status of salmonella,listeria monocytogens in food of Hengshui at 2010,and provide scientific basis for monitoring food poisoning and food-borne pathogenic bacteria.Method Based on the annual work manual of national food-borne pathogenic bacteria monitoring network in 2010 and carried out pathogenic bacteria separation and serology and biochemical detection to salmonella,staphylococcus aureus,listeria monocytogens,enterohemorrhagic escherichia coli in 3 kinds of food.Results 13 pathogenic bacteria strains were detected from 150 samples,and the total detection rate was 8.7%.Fresh meat,cooked meat and rice and flour products can detect pathogenic bacteria.Pathogenic bacteria detection rate of fresh meat was 14%.Conclusions We should strengthen the food hygiene management,and ensure food security.