化学
甲酰胺类
胺化
催化作用
铜
产量(工程)
有机化学
组合化学
还原胺化
材料科学
冶金
作者
Yunpeng Dong,Zhenzhen Peng,Lin Chen,Ying-Chih Lin,M. D. Lan,Wu Ch,Zhichuan Shi,Guowei Deng,Bing He
出处
期刊:Tetrahedron
[Elsevier]
日期:2024-04-01
卷期号:155: 133916-133916
标识
DOI:10.1016/j.tet.2024.133916
摘要
A facile, efficient, and practical method for copper-catalyzed direct amination of maleimides and quinones with formamides in the presence of an oxidant KIO3 has been developed. It allows a facile access to a wide range of functionalized molecules with privileged scaffolds in drugs and natural products such as maleimides and quinones. A variety of substituted 3-amino-maleimides and 2-amino-quinones were synthesized with moderate to excellent yield.
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