过氧化物酶
嗜酸性粒细胞过氧化物酶
生物化学
荧光
酪氨酸酶
化学
酶
生物
量子力学
物理
作者
Jiaying Zhou,Yujie Geng,Zhuo Wang
出处
期刊:Methods
[Elsevier BV]
日期:2023-01-10
卷期号:210: 20-35
被引量:6
标识
DOI:10.1016/j.ymeth.2023.01.002
摘要
Oxidases and peroxidases are two subclasses of oxidoreductases. The abnormal expression of oxidases (such as tyrosinase, cytochrome P450 oxidases, and monoamine oxidases) and peroxidases (such as glutathione peroxidase, myeloperoxidase, and eosinophil peroxidase) is relative with some diseases. Therefore, the analysis of oxidases and peroxidases is great important for disease diagnosis and treatment. Fluorescent probes present simple protocol, high sensitivity and good stability in sensing field. Molecule fluorescent probes are constructed with chemical groups that tunes their fluorescence emission in response to binding events, chemical reactions, and the surrounding environment. A fluorescent probe is an efficient tool for visualizing the activity of enzymes in living organisms on the basis of its high specificity, sensitivity, and noninvasiveness characteristics. In this review, we focus on the sensing of oxidases and peroxidases by molecule fluorescent probes, and hope to bring new insight to wide researchers about oxidases and peroxidases in biological samples.
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