微生物群
寄主(生物学)
生物
肠道菌群
人类健康
肠道微生物群
人体微生物群
计算生物学
生物信息学
遗传学
医学
免疫学
环境卫生
出处
期刊:Life Sciences
[Elsevier]
日期:2023-01-01
卷期号:312: 121265-121265
被引量:1
标识
DOI:10.1016/j.lfs.2022.121265
摘要
Human responses to the same diets may vary to a large extent, depending on the complex diet-host-microbiota interactions. Recent scientific advance has indicated that this diet-host-microbiota interaction could be quantified to develop strategies for improving individual health (personalized nutrition). Compared to the host related factors (which are difficult to manipulate), the gut microbiome is more readily modulated by dietary exposures and has important roles in affecting human health via the synthesis of various bioactive compounds and participating in the digestion and absorption process of macro- and micronutrients. Therefore, gut microbiota alterations induced by diets could possibly be utilized to improve human health in a targeted manner. However, limitations in the processing and analysis of 'big-data' concerning human microbiome still restrict the translational capacity of diet-host-microbiota interactions into tools to improve personalized human health. In the current review, recent advances in terms of understanding the specific diet-host-microbiota interactions were summarized, aiming to help the development of strategies for personalized nutrition.
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