Transition‐Metal‐Catalyzed Directed C−H Functionalization in/on Water

Abstract Directing group assisted C−H bond functionalization using transition‐metal‐catalysis has emerged as a reliable synthetic tool for the construction of regioselective carbon‐carbon/heteroatom bonds. Off late, “in/on water directed transition‐metal‐catalysis”, though still underdeveloped, has appeared as one of the prominent themes in sustainable organic chemistry. This article covers the advancements, mechanistic insights and application of the sustainable directed C−H bond functionalization of (hetero)arenes in/on water in the presence of transition‐metal‐catalysis.