Summary of the Best Evidence for Mechanical Prophylaxis of Venous Thromboembolism In Adult Hospitalized Patients

Objectives: To obtain domestic and international evidence on mechanical prophylaxis of venous thromboembolism in adult inpatients and to summarize the best evidence.Methods: By the "6S" pyramid model, domestic and international guidelines and databases were systematically searched, with a time frame from the establishment of the database to January 31, 2023, and evidence with a more recent time frame was preferred.Two researchers (Master) with evidence-based training independently searched, screened, and evaluated the evidence, and a third (Doctor) reviewed, extracted, and graded the evidence for the included literature.Results: A total of 3590 documents were obtained from the Chinese and English databases retrieved, and after screening and evaluation, 22 documents were finally included, which were summarized to form 7 key elements and 28 pieces of best evidence.Conclusions: This study summarizes the evidence related to mechanical prophylaxis of venous thromboembolism in hospitalized patients to provide an evidence-based basis for standardizing clinical mechanical prophylaxis, and healthcare professionals need to select the best evidence in a targeted manner by taking into account the characteristics of the hospital and the clinical environment. Journal of Clinical Medicine: Current ResearchYue Zhao and Yinglan Li, et al.www.clinicalmedicinecr.com 100,000, and an incidence of DVT and PTE of approximately 0.87-1.82cases per 1,000 person-years (p.y.) and 0.45-0.95cases per 1,000 p.y., respectively, in the Western world; in the U.S., the annual number of 300,000-600,000 cases of VTE in the U.S. 2 In Asian populations, Japan reported 3 an annual incidence of 10.0/100,000 patients with VTE.A Korean study 4 showed that the annual incidence of VTE increased to 42.2/100,000 cases in 2016.An observational study from the University of Hong Kong 5 concluded that the incidence of VTE increased to 48.3 / 100,000 in 2016, with an increasing trend in those aged 75 years or older.