Diffuse Uptake of 68Ga-Pentixafor in the Breasts During the Ovulatory Phase in a Patient With SAPHO Syndrome

Abstract We report a case of a woman with SAPHO syndrome who exhibited increased tracer uptake in the sternal angle on a 99m Tc-MDP bone scan. This patient was enrolled in a 68 Ga-pentixafor PET/CT trial for inflammatory diseases. The PET/CT showed no abnormal tracer uptake in the sternal angle. Unexpectedly, diffuse uptake of 68 Ga-pentixafor was observed in both breasts, which might be due to hormonal stimulation because the woman underwent the 68 Ga-pentixafor PET/CT scan during the ovulatory phase.