ARF7/19 activate CRF3 in response to cold via Aux/IAA degradation

Cold induces degradation of Aux/IAA proteins through the ubiquitin-proteasome pathway, releasing AUXIN RESPONSE FACTOR7 (ARF7) and ARF19 from Aux/IAA-mediated repression, leading to activation of CYTOKININ RESPONSE FACTOR 3 (CRF3) expression under cold stress. This study reveals a regulatory mechanism integrating cold signaling and auxin response in the control of CRF3 expression.