Integration of habitat radiomics and traditional radiomic features for predicting pathological complete response in esophageal squamous cell carcinoma following neoadjuvant immunotherapy and chemotherapy: a multicenter comparative study

This study demonstrates that Habitat Radiomics features provide significant advantages over traditional Radiomics in predicting immunotherapy response in ESCC patients. The combined model, integrating both feature sets, shows exceptional predictive performance, with promising clinical applications in personalized treatment strategies. Future research will explore the broader applicability of this model across different cancer types and its integration with additional biomarkers to further enhance prediction accuracy.