Manicol, an aromatic sesquiterpene from Dulacia guianensis(Liriosma cf. acuta)
倍半萜
立体化学
化学
戒指(化学)
有机化学
作者
Judith Polonsky,Zoīa Varon,Henry Jacquemin,Dervilla M. X. Donnelly,Mary J. Meegan
出处
期刊:Journal of the Chemical Society日期:1980-01-01卷期号:: 2065-2065被引量:8
标识
DOI:10.1039/p19800002065
摘要
A eudesmane-type sesquiterpene acid with an aromatic A-ring isolated from a Guyanan tree Dulacia guianensis(Olacacea) was assigned a structure and an absolute stereochemistry (1) on the basis of spectroscopic evidence and partial synthesis. The isolate had moderate antileukaemic activity in P–388 lymphocytic leukaemia.