Artificial Bacterial Flagella for Remote‐Controlled Targeted Single‐Cell Drug Delivery

SmallVolume 10, Issue 10 p. 1953-1957 Communication Artificial Bacterial Flagella for Remote-Controlled Targeted Single-Cell Drug Delivery Rami Mhanna, Corresponding Author Rami Mhanna Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandE-mail: rami.mhanna@dep.uminho.ptSearch for more papers by this authorFamin Qiu, Famin Qiu Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this authorLi Zhang, Li Zhang Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong SAR, ChinaSearch for more papers by this authorYun Ding, Yun Ding Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this authorKaori Sugihara, Kaori Sugihara Laboratory of Biosensors and Bioelectronics, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this authorMarcy Zenobi-Wong, Marcy Zenobi-Wong Cartilage Engineering + Regeneration, ETH Zurich, Zurich, CH-8093 SwitzerlandSearch for more papers by this authorBradley J. Nelson, Bradley J. Nelson Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this author Rami Mhanna, Corresponding Author Rami Mhanna Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandE-mail: rami.mhanna@dep.uminho.ptSearch for more papers by this authorFamin Qiu, Famin Qiu Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this authorLi Zhang, Li Zhang Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong SAR, ChinaSearch for more papers by this authorYun Ding, Yun Ding Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this authorKaori Sugihara, Kaori Sugihara Laboratory of Biosensors and Bioelectronics, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this authorMarcy Zenobi-Wong, Marcy Zenobi-Wong Cartilage Engineering + Regeneration, ETH Zurich, Zurich, CH-8093 SwitzerlandSearch for more papers by this authorBradley J. Nelson, Bradley J. Nelson Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092 SwitzerlandSearch for more papers by this author First published: 10 March 2014 https://doi.org/10.1002/smll.201303538Citations: 155Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract An approach for batch preparation of liposome-functionalized microdevices is demonstrated for remotely controlled single-cell drug delivery. The liposome functionalized artificial bacterial flagella exhibit corkscrew swimming in 3D with micrometer positioning precision by applying an external rotating magnetic field. The devices are also capable of delivering water-soluble drugs to single cells in vitro. Citing Literature Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description smll201303538-sup-0001-S1.pdf1.5 MB Supplementary smll201303538-sup-0002-S2.wmv278.5 KB Supplementary Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume10, Issue10May 28, 2014Pages 1953-1957 RelatedInformation