Visible-Light-Induced FeCl 3 -Promoted Dehydroxypropylative Selenylation of Acyclic Alcohols

-promoted dehydroxypropylative selenylation of tertiary acyclic alcohols with diselenides has been developed for constructing unsymmetrical monoselenides. This protocol enables direct C-C bond cleavage and concomitant C-Se bond formation without the need for an additional photocatalyst. The reaction exhibits a broad substrate scope across various diselenides and alcohols and is amenable to gram-scale synthesis. Mechanistic studies support a radical pathway initiated through ligand-to-metal charge transfer (LMCT) upon light irradiation.