医学
2019年冠状病毒病(COVID-19)
爆发
内科学
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
大流行
2019-20冠状病毒爆发
病历
疾病严重程度
回顾性队列研究
重症监护
重症监护医学
病毒学
疾病
传染病(医学专业)
作者
Deniz Çekiç,Mehmet Emir Arman,Ahmed Cihad Genç,Kubilay İşsever,İlhan Yıldırım,Ahmed Bilal Genç,Hamad Dheir,Selçuk Yaylacı
摘要
No effective treatment has yet been found for SARS-Cov-2, which caused a pandemic outbreak in 2019. It is crucial to detect the progression of COVID-19 in patients as early as possible. Fibrinogen to albumin ratio (FAR) has been used as a new inflammatory marker. We aimed to find out whether the use of the FAR as a predictor of mortality in COVID-19 patients provides clinical benefit.Data from 590 patients with COVID-19 from March 15, 2020 to January 15, 2021 in medicine wards and intensive care units (ICU) were retrospectively analysed. Demographic data and other laboratory markers were collected from the electronic medical records. Relationship between FAR was investigated between patients in the survivor/non-survivor patients.The mean FAR levels in patients who were non-survivor was 24.44 ± 30.3 (n = 272 and 11.29 ± 6.29 (n = 275) (P = .000) in patients survivor COVID-19 infection. In ROC curve for FAR, the threshold FAR that may pose a risk for mortality was determined as 13.84 ((AUC: 0.808 (0.771-0.844)); 74.9% sensitivity, 74.6% specificity; P = .000)).As a result of this study, increased FAR were found to be important markers in determining the mortality levels in COVID-19 patients.
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